ISC 2026 Class 12 Biology Question Paper with Solutions PDF (March 6)

CISCE 12th Biology (Theory) Exam 2026: Overview

The table below shows all the important details about the ISC 12th Biology Exam 2026.

How to Download ISC 12th Biology Question Paper 2026 PDF

Students can download the ISC Class 12 Biology Question Paper 2026 PDF by following these simple steps:

1. Visit the section titled “ISC 12th Biology Question Paper 2026” on this page.

2. Click on the available download link of the question.

3. You will be redirected to a new page of Careers360, which will have the Biology Question paper PDF.

4. Click on the ‘Free Download’ button.

5. Log in or sign up, if required (the process is simple and quick).

6. The ISC 12th Biology question paper PDF will begin downloading.

CISCE 12th Biology (Theory) Question Paper 2026: Download PDF

The ISC Class 12 Biology Question Paper 2026 PDF is now uploaded in the table given below.

ISC 12th Biology Answer Key 2026 (Unofficial)

The Biology teachers have released an unofficial ISC Class 12 Biology Answer Key 2026 in the table below. While it is not issued by CISCE, it is very useful for a quick self-evaluation. With the help of the answer key, students can match their responses with the suggested answers and calculate their expected marks.

ISC 12th Biology Answer Key 2026

Given below are the answers to the objective questions from the ISC Class 12 Biology Question Paper 2026. For the complete answer key of all sections, students can refer to the link given in the table above.

(i) Mycobacterium tuberculosis

(ii) Xenopsylla (rat flea)

(iii) 24 chromosomes

(iv) HpyDC3II

(v) Phenylalanine hydroxylase

(vi) Death rate = 70/770 × 1000 = 90.9 per thousand per month

(vii) Biological control using ladybird beetles (predators of aphids) or introducing parasitoids like Aphidius

(viii) Total pollen mother cells = 50. Each PMC produces 4 pollen grains, and each anther has 2 thecae with 2 microsporangia each = 4 microsporangia.

Total pollen grains = 50 × 4 = 200

25% develop pollen tubes = 200 × 25/100 = 50 pollen grains

(ix) (b) Only (P), (R), and (S)

(x) (c) Blockage of lymph vessels

(xi) (a) Both Assertion and Reason are true, and Reason is the correct explanation for Assertion.

(xii) (c) Assertion is true, and Reason is false.

(xiii) 1/4 (25%) of the flowers will be in the terminal position

(xiv) Myasthenia gravis

(xv) (a) Intra Uterine Insemination (b) Severo Ochoa

(xvi) Tinea (Trichophyton)

(xvii) Interleukin

ISC Class 12 Biology Exam Pattern 2026

A clear idea of the ISC Class 12 Exam Pattern 2026 of Biology helps you prepare in a focused way and handle the paper confidently on exam day.

The ISC Class 12 Biology exam generally consists of two components:

• Theory (Written Paper): 70 Marks

• Practical (Laboratory Work & Viva): 30 Marks

The theory paper carries a total of 70 marks, and questions are framed from all five major units of the syllabus. Below is the unit-wise weightage for the ISC Class 12 Biology theory examination:

Important Topics for ISC 12th Biology 2026

While the whole syllabus is important, students should pay special attention to the following areas:

Thorough command over these chapters is extremely helpful for both board exams and competitive exams like NEET.

Preparation Tips for ISC 12th Biology Exam 2026

Here are some practical, exam-focused tips students can follow:

• Complete the ISC-prescribed textbooks first i.e Read each chapter line by line from the recommended ISC Biology books. Many direct and indirect questions are framed from textbook content.

• Prepare short notes for definitions, key terms, cycles, and processes. These are very useful during last-minute revision.

• Practice labelled diagrams daily because diagrams are an integral part of Biology. Practice neat, clearly labelled diagrams for topics like anatomy, physiology, reproductive structures, and ecological cycles.

• Revise genetic crosses and biotechnology steps carefully

• Pay extra attention to Mendelian crosses, test crosses, dihybrid crosses, and important techniques such as PCR, cloning, DNA fingerprinting, recombinant DNA technology, etc.

• Solve previous years’ ISC Biology papers. Regularly attempt past question papers and specimen papers under timed conditions. This builds speed, accuracy, and familiarity with the pattern.

• Use the last 10–15 minutes wisely to:

  • Recheck attempted questions.

  • Ensure diagrams are properly labelled.

  • Correct any spelling mistakes in scientific terms.

Why Solving Previous Years’ Question (PYQ) Papers Is Important

Solving previous years’ questions of the ISC Question Papers of Biology is very help very helpful for students because

• It improves answer-writing skills i.e students can learn how much detail to write for 2‑mark, 3‑mark, and 5‑mark questions.

• Solving PYQs and sample papers helps students understand which topics are the most repeated and the overall difficulty level of questions.

• Attempting PYQs within the allotted time trains students to manage time in the real exam without rushing.

• Regular practice of PYQs makes the real exam feel like just another mock test.

Related Links-

• ISC 12th Home Science Question Paper 2026

• ISC 12th Chemistry Question Paper 2026

• ISC 12th English Question Paper 2026