Biomolecules class 12th notes- Free ncert class 12 Chemistry Chapter 14 Notes- Download PDF

Biomolecules class 12th notes- Free ncert class 12 Chemistry Chapter 14 Notes- Download PDF

Shivani PooniaUpdated on 02 Sep 2025, 11:48 AM IST

How do simple sugars give you energy? What makes food nutritious? How do proteins build your body? Biomolecules uncover the chemistry behind carbohydrates, proteins, nucleic acids, and enzymes, which form the foundation of every living organism; they play a unique role in the functionality and health of organisms. Biomolecules, or biological molecules, are made by living organisms and are crucial for various life functions. All biomolecules are naturally occurring compounds. They include large macromolecules, such as proteins, carbohydrates, lipids, and nucleic acids, as well as smaller molecules, including vitamins and hormones. These organic molecules are key to all life forms and support many biological processes. From simply eating food to the occurrence of all the processes inside our body, Biomolecules play an important role.

This Story also Contains

  1. NCERT Notes for Class 12 Chapter 10 Biomolecules: Download PDF
  2. NCERT Notes for Class 12 Chapter 10 Biomolecules
  3. Biomolecules Previous Years' Questions With Answers
  4. NCERT Class 12 Notes Chapter-Wise
  5. NCERT Exemplar Solutions Subject-Wise
  6. NCERT Solutions Subject-Wise
  7. NCERT Books and Syllabus
Biomolecules class 12th notes- Free ncert class 12 Chemistry Chapter 14 Notes- Download PDF
Biomolecules

The NCERT Notes for Class 12 Chemistry will be helpful for a quick revision of topics. These NCERT notes for Chapter 10 Biomolecules are designed by our subject experts, which ensures the credibility of the content provided. It becomes difficult and time-consuming for students to read the NCERT textbooks point-to-point. So, to solve this problem, we are providing these NCERT notes that cover all the topics and concepts provided in the NCERT textbook in a very clear and comprehensive way. These Biomolecules class 12 notes are also valuable resources for various competitive exams like JEE, NEET, etc. Also, check the NCERT Solutions for all the chapters

Also Read:

NCERT Solutions for Class 12 Chemistry Chapter 10 Biomolecules

NCERT Exemplar Solutions Class 12 Chemistry Biomolecules

NCERT Notes for Class 12 Chapter 10 Biomolecules: Download PDF

Download the Biomolecules Class 12 NCERT Notes pdf to access clear explanation, important reactions. These NCERT notes cover all the key concepts of Biomolecules. You can download the PDF from the button given below:

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NCERT Notes for Class 12 Chapter 10 Biomolecules

NCERT Class 12 Chapter 10 Chemistry includes topics like the structure, classification, and functions of essential biomolecules like carbohydrates, proteins, nucleic acids, and vitamins. It shows how biomolecules are linked to our health and influence everything from what we eat to the medicines we take. Carbohydrates provide energy for everyday activities, Proteins are essential for growth, Lipids serve the purpose of energy storage, and Nucleic Acids, like DNA and RNA, are essential for genetic information transmission. Class 12 Chapter 10 Biomolecules notes PDF is the best resource for quick revision, also they help build a clear understanding of fundamental principles and their real-life applications.

Biomolecules

Biomolecules are organic substances that form a basis for the growth and maintenance of the human body.

Biomolecules discussed here are carbohydrates, proteins, enzymes, vitamins, nucleic acids, and hormones.

A) Carbohydrates

  • Manufactured in plants by performing photosynthesis.
  • Optically active polyhydroxy aldehydes/ polyhydroxy ketones.
  • Food, clothing, and shelter.

Classification of carbohydrates:

Classification of carbohydrates is based on their structure and the number of sugar units they contain. You can download these Class 12 Chapter 10 Biomolecules notes PDF for offline access, making it easier to study at your own pace and convenience.

1. Monosaccharides

Monosaccharides are the simplest carbohydrates that cannot be hydrolyzed into simpler compounds.

Examples are glucose, fructose, and ribose.

General formula- (CH2O)5

Glucose:

Present in honey and fruits.

Belongs to D-family.

  • Preparation of glucose

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a)From sucrose-

$\mathrm{C}_{12} \mathrm{H}_{22} \mathrm{O}_{11}+\mathrm{H}_2 \mathrm{O} \xrightarrow{\mathrm{H}^{+}} \mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6+\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6$

b)From starch-

$\left(\mathrm{C}_6 \mathrm{H}_{10} \mathrm{O}_5\right)_{\mathrm{n}}+\mathrm{nH}_2 \mathrm{O} \xrightarrow[393 \mathrm{~K}, 2-3 \text { bar }]{\mathrm{H}^{+}} \mathrm{nC}_6 \mathrm{H}_{12} \mathrm{O}_6$

Structure Of Glucose

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Here are a few reactions to find the structure of glucose-

a)Straight chain structure-

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b)Presence of five hydroxyl groups-

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c)Presence of an aldehyde group-

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d)Oxidation of glucose-

Oxidation of glucose indicates the presence of the primary alcoholic group.

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e)Open chain structure of Glucose-

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D-(+)-Glucose

The cyclic structure of glucose

Limitations of open chain structure of glucose-

  • Glucose does not undergo some of the characteristic reactions of aldehydes.
  • No reaction with ammonia
  • No reaction with hydroxylamine.

(+)-Glucose exists in two stereoisomeric forms i.e., α-D-glucose and β-D-Glucose.

Mutarotation-the two forms of glucose, convert into each other at equilibrium when glucose is dissolved in water and allowed to stand.

Anomers

Cyclization in the structure of glucose has been observed by the formation of hemiacetal between -CHO group and -OH group. On C5 carbon.

Optical isomers exist when configuration around only one of the carbons C1 takes place. These are known as anomers.

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α-D-glucose β-D-Glucose

Fructose

Fructose is obtained when disaccharides are hydrolyzed. Fructose has a six-member hemiacetal ring structure.

Structure of fructose

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α-D-fructose β-D-fructose

Haworth structure of fructose

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α-D-fructose β-D-fructose

2. Disaccharides

These are the types of carbohydrates that give more than one (can be the same or not) monosaccharide.

Examples-

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3. Polysaccharides

These are polymer compounds that are formed by many numbers of monosaccharide units which are joined together by glycosidic linkages.

a)Starch

  • Found in plants.
  • Found in wheat, rice, maize, potatoes, barley, etc.
  • Starch reacts with iodine solution to give a blue color.
  • It is a non-reducing saccharide.
  • Does not reduce Fehling’s solution.

b)Amylose

  • Linear polymer
  • It contains 200-300 α-D-glucose units linked together by glycosidic linkages.
  • Molecular mass (10,000-500,000)

c)Amylopectin

  • It is a highly branched polymer.
  • Do not react with iodine solution to give a blue color.

d)Cellulose

  • It is the most abundant organic polymer found on earth.
  • It is a straight-chain polymer joined by β-glycosidic linkages.
  • Used in the manufacturing of paper, textiles, and plastic industries.

e)Glycogen

  • It is a polysaccharide found in animal cells occurring in muscles, and the liver.
  • It is known as animal starch.
  • It is a polymer made up of a thousand glucose units.

Importance of carbohydrates

  • Plays a major role for both plants as well as animals.
  • Carbohydrates are the major source of energy (except cellulose)
  • Carbohydrates store energy for the functioning of living organisms.
  • Carbohydrates are used as raw materials in the production of textiles, papers, lacquers, breweries, etc.

B) Proteins:

All living cells are made up of biomolecules having a high molecular mass, known as amino acids. Students can also refer NCERT Solutions for Class 12 Chemistry Chapter 10 Biomolecules to understand these concepts better through a series of solved questions.

1. Amino acids

Amino acids are the building block units of proteins. These are the organic compounds that contain amino as well as a carboxyl group.

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The above unit may be attached to any other carbon atom other than that of the -COOH group.

2. Classification of Amino Acids

Amino acids can be broadly classified as – acidic, basic, or neutral.

Neutral amino acids- These are the amino acids that contain an equal number of amino and carboxyl groups. Examples- glycine, alanine, valine, etc.

Acidic neutral acids- These are amino acids that contain more carboxyl groups than amino groups. Examples- are aspartic acid, asparagine acid, and glutamic acid, which contain two -COOH groups and one -NH3 group.

Basic amino acids- These contain more amino groups than carboxyl groups. Examples- lysine, arginine, and histidine.

3. Structure of Proteins

Amino acids exist as zwitterion which is dipolar.

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The basic nature of zwitterion is due to -COO- ion.

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The acidic character of zwitterion is due to the -NH3+ group.

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Peptide linkage- When two or more amino acids condense, the resulting -CO-NH- link is called peptide linkage of the peptide bond.

The structure of proteins is classified into four hierarchical levels based on different structural parameters such as the folding patterns, the sequence of amino acids, 3D conformation, and functional arrangement.

  • Primary structure of proteins- amino acids are linked in one or more polypeptide chains, which are known as the primary structure of proteins.
  • Secondary structure of proteins- the folding and arrangement of polypeptide chains give the shape or conformation of the protein.
  • The secondary structure can be of α-helix structure type or β-pleated sheet structure.
  • Tertiary structure- the tertiary structure of the protein arises due to the folding, bending, and coiling, which results in three-dimensional structures.
  • Quaternary structure- many of the proteins exist as a grouping of two or more polypeptide chains. These polypeptide chains are called the sub-units.

Proteins can be classified into two types based on their molecular shape.

(a) Fibrous proteins: When the polypeptide chains run parallel and are held together by hydrogen and disulfide bonds, then fiber-like structure is formed. Such proteins are generally insoluble in water. Some common examples are keratin (present in hair, wool, silk) and myosin (present in muscles), etc

4. Denaturation of Proteins

Proteins can be denatured (physical changes and biological changes) but there is no chemical change in the protein structure.

Denaturation can arise due to many factors such as changes in temperature, pH, or certain chemical agents.

Enzymes

Enzymes are biological catalysts that catalyze biochemical reactions in living organisms. For example- hydrolysis of maltose is catalyzed by maltase.

Mechanism of enzyme

The mechanism is given as

  1. The enzyme (E) binds to the substrate(s)

E+S→ES

  1. Product Formation

ES→EP

  1. Products released from the above complex.

EP→E+P

C) Vitamins

These are the biomolecules that are not produced by the body and hence, need to be supplied in small amounts for necessary biological functions of the body.

There are A, B, C, D, E, and K vitamins.

  • Classification of Vitamins

Water-soluble vitamins- water-soluble vitamins are vitamin B, vitamin C, etc.

These vitamins need to be supplied to the body from time to time.

Fat-soluble vitamins- vitamins that are only soluble in fat are called fat-soluble vitamins. A, D, E, and, K vitamins are soluble in fat.

Vitamin deficiency-associated diseases:

Vitamin A - Night blindness, Xeropthalmia

Vitamin (Thiamine) B1 - Beriberi

Vitamin (Riboflavin) B2 - Cheilosis

Vitamin (Niacin) B3 - Pellagra

Vitamin (Pyridoxine) B2 - Convulsions , Anaemia

Vitamin B12 - Pernicious anaemia

Vitamin C (Ascorbic acid) - Scurvy

Vitamin D - Rickets ( in children)

Osteomalacia ( in adults )

Vitamin E - Increased RBC fragility, muscular weakness

Vitamin K - Poor blood clotting

D) Nucleic Acids

  • Nucleic acids are polymers that are present in all human bodies.
  • Nucleic acids play an important role in the development and reproduction of all life forms.
  • Nucleic acids have nucleotides as their repeating units.

There are two types of nucleic acids-

DNA (deoxyribonucleic acid) and RNA (ribonucleic acid)

  1. Chemical composition of nucleic acids-

Nucleotides consist of three chemical components such as a heterocyclic base, a five-carbon sugar, and a phosphate group.

  1. Structure of Nucleic acids-

a) Nitrogen-containing heterocyclic base- Purines and pyrimidines are two types of heterocyclic bases. Example- Adenine and guanine are purines. Cytosine, thymine, and uracil are pyrimidines.

b) Sugars- the two types of sugars are RNA and DNA.

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c) phosphate group- nucleotides are joined by these linkages.

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d)Nucleoside- When a nitrogen base is attached to a sugar molecule a nucleoside unit is produced.

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e) Nucleotide-

Base+Sugar+phosphate →nucleotide

  1. The biological function of nucleic acids-

Some of the biological functions of nucleic acids are-

Replication- It is the property of a biomolecule to synthesize another molecule.

For example, DNA has a unique property to replicate itself.

Protein synthesis- genetic information stored in DNA in a specific base sequence is expressed in the form of a specific base sequence.

E) Hormones

Hormones are molecules that act as intercellular messengers. These are produced by endocrine glands in the body and are poured directly in the blood stream, which transports them to the site of action.

In terms of chemical nature, some of these are steroids, e.g., estrogens and androgens; some are poly peptides for example insulin and endorphins; and some others are amino acid derivatives such as epinephrine and norepinephrine. Hormones have several functions in the body. They help to maintain the balance of biological activities in the body.

Biomolecules Previous Years' Questions With Answers

Selected Previous Years Questions with Answers of Chapter 10 Class 12 Chemistry Biomolecules are given below that help students revise important exam topics and understand the type of questions asked.

Question 1. Explain what is meant by:

(i) Peptide linkage

(ii) Glycosidic linkage

Answer:

(i) Peptide linkage: In this type of linkage, an amide bond is formed between the –COOH group of one amino acid and the –NH2 group of another, releasing a molecule of water.

(ii) Glycosidic linkage: By the elimination of water, an ether (–O–) bond is formed between two monosaccharide units.

Question 2. Name two water‑soluble vitamins, their sources, and deficiency diseases.

Answer:

Vitamin B2: Found in milk, yeast, and leafy vegetables. Deficiency causes glossitis, dermatitis.

Vitamin C: Found in citrus fruits and green veggies. Deficiency leads to scurvy.

Question 3. Name the four bases in DNA. Which one is not present in RNA?

Answer:

Four bases of DNA: Adenine, Guanine, Cytosine, Thymine.

Thymine is not present in RNA; it is replaced by Uracil.

NCERT Exemplar Solutions Subject-Wise

NCERT Class 12 exemplar solutions for each subject are given below:

NCERT Books and Syllabus

The NCERT books and syllabus links for class 12 are given below:

Frequently Asked Questions (FAQs)

Q: How to study Class 12 biomolecules notes in the right manner?
A:

Student should go through Class 12 Chemistry chapter 10 notes containing all the headings and subheadings with their brief explanation and solve questions from each topic.

Q: What are proteins made up of?
A:

Proteins are made up of amino acids. Amino acids are organic molecules that contain an amino group, a carboxyl group , and a side chain, all attached to a central carbon atom. 20 common amino acids are used to build proteins.

Q: Why are biomolecules important to study in Chemistry?
A:

Understanding biomolecules is crucial because they are the foundation of all biological processes. Studying their structure, properties, and reactions helps us understand how living organisms function at a molecular level. This knowledge is then used in medicine, agriculture, biotechnology, and other scientific fields.

Q: What are the four main types of biomolecules?
A:

 The four major types of biomolecules are:

  • Carbohydrates
  • Proteins
  • Nucleic acids
  • Lipids
Q: How do you classify carbohydrates?
A:

Carbohydrates are classified into three main categories based on the number of sugar units they contain:

  • Monosaccharides: These are the simplest sugars, consisting of a single sugar unit. Examples include glucose, fructose, and galactose.
  • Disaccharides: These are composed of two monosaccharides joined together by a glycosidic bond. Examples include sucrose (glucose + fructose), lactose (glucose + galactose), and maltose (glucose + glucose).
  • Polysaccharides: These are complex carbohydrates made up of many monosaccharide units linked together. Examples include starch, glycogen, and cellulose.
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