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Blood: Type, Definition,Composition, Functions, Components

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Blood: Type, Definition,Composition, Functions, Components

Edited By Team Careers360 | Updated on Feb 07, 2024 12:14 PM IST

Blood is a bodily fluid found in the circulatory systems of humans and other animals that carries metabolic waste products away from the cells as well as vital nutrients and oxygen to the cells. Peripheral blood and the blood cells it contains, peripheral blood cells, are terms used to describe the blood in the circulatory system.

What is Blood?

Floating in blood plasma are the blood cells that makeup blood. Proteins, glucose, hormones, mineral ions, carbon dioxide (plasma is the principal medium for excretory product movement), and blood cells themselves are all found in plasma, which makes up 55% of blood fluid and is 92% water by volume.

The primary protein in plasma, albumin, controls the blood's colloidal osmotic pressure.

The majority of the cells in vertebrate blood are red blood cells. These have haemoglobin, a protein that contains iron and speeds up the delivery of oxygen by reversibly binding to it and boosting its solubility in blood. Contrarily, most of the extracellular transportation of carbon dioxide occurs as the bicarbonate ion in plasma.

Functions of Blood

  • Provision of oxygen to tissues (bound to haemoglobin, which is carried in red cells).

  • There is easy access to nutrients like glucose, amino acids, and fatty acids (in the blood or bound to plasma proteins, like blood lipids).

  • White blood cell circulation and antibody-based detection of foreign substances are two examples of immunological processes.

  • Coagulation, the procedure used to control bleeding after a blood vessel ruptures, changes blood from a liquid to a semisolid gel.

  • Messenger processes, including hormone delivery and tissue damage signalling.

Blood Conditions

Haemorrhage (bleeding): It may be evident when blood leaks from blood vessels, such as when a cut breaks through the skin. Internal bleeding, such as that which occurs after a car accident or into the intestines, may not be immediately noticeable.

Leukaemia: A type of blood cancer in which the white blood cells circulate through the blood and grow abnormally. The aberrant white blood cells make infection-related illnesses more common than usual.

Lymphoma: A type of blood cancer in which organs such as lymph nodes and other tissues become inappropriately colonised by white blood cells. Organ failure may eventually result from growing tissues and disruption of blood functions.

Hemochromatosis: A condition where the blood has high quantities of iron. Diabetes and difficulties with the liver are brought on by iron buildup in the pancreas, liver, and other organs.

Sickle cell disease: Red blood cells that periodically lose their correct form due to a hereditary issue (appearing like sickles rather than discs). Blood cells with abnormal shapes collect in tissues, harming organs and producing discomfort.

Disseminated intravascular coagulation (DIC): An unregulated process that causes bleeding and clotting to occur simultaneously in tiny blood vessels. Cancer or serious infections are the usual causes of DIC.

Deep venous thrombosis (DVT): A blood clot that commonly occurs in a deep vein in the leg. Due to the possibility that they could become dislodged and move to the lungs, causing a pulmonary embolism, DVTs are risky (PE).

Myocardial infarction (MI): When a blood clot develops unexpectedly in one of the coronary arteries that provide blood to the heart, a myocardial infarction, often known as a heart attack, occurs.

Components of Blood

  • Plasma: The plasma component of blood can be separated by quickly spinning a tube of whole blood in a centrifuge. Plasma stays at the top of the tube, generating a yellow layer, while the heavier cells and platelets move to the bottom, forming red and white layers.

  • Red Blood Cells: Erythrocytes, often known as red blood cells, are specialised cells that travel throughout the body and carry oxygen to tissues. Red blood cells in humans are tiny, biconcave, and do not mature with mitochondria or a nucleus.

  • Platelets: The cell fragments known as platelets, or thrombocytes, are essential for blood coagulation. They are created when massive cells known as megakaryocytes split apart, each of which produces 200020002000 - 300030003000 platelets as it does so.

  • White Blood Cells: Less than 1% of the blood's cells are white blood cells, also known as leukocytes, which are far less frequent than red blood cells. Additionally, they play an utterly distinct role from red blood cells, being primarily responsible for immunological responses and identifying and combating foreign invaders like bacteria and viruses.

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Composition of Blood

The cells and cell fragments from a blood sample are separated from the liquid intercellular matrix when it is spun in a centrifuge. The generated elements are packed in the bottom of the tube by centrifugal force since they are heavier than the liquid matrix. The plasma, which makes up around 55% of the blood volume and is the pale yellow liquid on top, is also known as the hematocrit, or packed cell volume, of red blood cells (PCV). Between plasma and red blood cells, a thin covering of white blood cells and platelets is known as the "buffy coat."

Blood Vessels

Our body's blood travels through blood arteries, which act as conduits. They create a circuit-like closed loop that starts and finishes at your heart. Your circulatory system is made up of blood vessels and heart vessels. About 60,000 miles of blood arteries make up your body.

Blood vessels come in three different varieties:

  • Blood is carried out from your heart through arteries.

  • Blood is returned to your heart through veins.

  • The tiniest blood channels, capillaries, link veins and arteries.

Importance of Blood

All of the body's components can continue to function by receiving oxygen and nutrition through the blood. The lungs, kidneys, and digestive system use the blood to transport carbon dioxide and other waste products for elimination from the body. Additionally, blood distributes hormones throughout the body and fights infections.

Blood Formation

  • The process through which the blood's formed components are created is known as hemopoiesis (hematopoiesis). The epiphyses of flat bones (such as the ribs and cranial bones), long bones (such as the humerus and femur), vertebrae, and the pelvis are where hemopoiesis occurs. Hemocytoblasts, which are hemopoietic stem cells, divide in the red bone marrow to create several types of "blast" cells. Each of these cells develops into a distinct developed element.

  • The production of erythrocytes, or erythropoiesis, starts with the development of proerythroblasts from hemopoietic stem cells. Several phases of development occur over the course of three to five days as ribosomes multiply and haemoglobin is produced.

  • Colony-stimulating factors (CSFs), which are hormones made by mature white blood cells, encourage leukopoiesis, the process of creating leukocytes. The division of the hemopoietic stem cells initiates the creation of each kind of white blood cell.

  • Megakaryoblasts, which are the precursors of thrombopoiesis, the production of platelets, are created from hematopoietic stem cells. Megakaryocytes, which are enormous cells with a massive, multilobed nucleus, are created when megakaryoblasts divide without cytokinesis. The plasma membrane then infolds into the cytoplasm, causing the megakaryocytes to split into pieces.

Haematology

The field of medicine known as haematology, or haematology in British English, is devoted to the research of blood-related disorders, including their causes, prognoses, treatments, and prevention. It entails treating conditions that have an impact on the development of blood and its constituent parts, including blood cells, haemoglobin, blood proteins, bone marrow, platelets, blood arteries, spleen, and the mechanism of coagulation. These conditions may include leukaemia, multiple myeloma, lymphoma, blood clots (thrombus), various bleeding disorders, and haemophilia. Medical technologists or medical laboratory scientists typically do the laboratory analysis of blood.

Frequently Asked Question (FAQs)

1. Why is our blood red?

Haemoglobin, or HEE-much-glow-bin, is an oxygen-carrying protein that is found in red blood cells. Haemoglobin absorbs oxygen in the lungs, giving blood its vivid red colour. Haemoglobin transports oxygen to various bodily areas as it circulates through the body.

2. What is blood level too low?

Low blood sugar is defined as less than 70 mg/dL. Check your blood sugar levels if you suspect a low. Treat it now if you are unable to check it first. Low blood sugar should always be treated right away because leaving it unattended might be harmful.

3. Where are blood cells made?

The bone marrow produces blood cells. The bone marrow is the soft, spongy substance in the middle of the bones. 95% of the blood cells in the body are produced by it. The pelvic bones, breast bones, and spine bones contain the majority of the bone marrow in the adult body.

4. What do blood cells do?

The primary function of red blood cells is to carry oxygen from the lungs to the body's tissues. Additionally, it returns carbon dioxide from the tissues, a waste product, to the lungs. Haemoglobin, a crucial protein present in red blood cells, is responsible for carrying oxygen from the lungs to every part of the body.

5. What is a complete blood cell count (CBC)?

The measurement of the size, quantity, and maturity of the various blood cells in a given volume of blood is known as a complete blood count (CBC). Numerous disorders involving either the creation or decomposition of blood cells can be detected with a CBC. An infection or disease process can be identified by changes in the blood cells' typical quantity, size, or maturity.

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